Juanjo Mosalini was born on April 29, 1972 in Buenos Aires. A musician, composer and teacher, he has been a recognised ambassador for the bandoneon for over 30 years, allowing the instrument to reach beyond the boundaries of Argentina, as far as France and indeed throughout the world. He studied the bandoneon with his father, and piano and harmony with Gustavo Beytelmann. He began his international career at the age of 18, and is one of very few bandoneon players to have performed at the Philharmonie de Paris, the Théâtre du Châtelet and the salle Gaveau in Paris, the Berlin & the Rotterdam Philharmonie, the Barbican Centre in London, the Massimo Theatre in Palermo, the Giuseppe Verdi Auditorium in Milan, the Accademia Chigiana in Siena, the Saint-Cecilia National Academy in Rome, the antique theatres in Athens and Orange, and the Mozart-Saal in Vienna.

Juanjo Mosalini has participated in the creation of several ensembles: the Bögeholz/Mosalini duo with guitarist Vicente Bögeholz, a duo combining interactivity and electronic music with jazz double bassist Olivier Sens, and the Mosalini Teruggi cuarteto together with composer and double bassist Leonardo Teruggi, pianist Romain Descharmes and violonist Sébastien Surel.

He is at present head of the tango department at the Gennevilliers Conservatoire.